Scientific Manager of Biostatistics - Fractional (Ad Hoc) Remote
Company: Penfield Search Partners
Location: Fairfield
Posted on: February 17, 2026
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Job Description:
Job Description Job Description Contact: Neisha Camacho/Terra
Parsons - No 3rd party candidates Scientific Manager of
Biostatistics Strategic, Per-Study Role with Flexibility and Growth
Potential We're seeking a specialized Scientific Manager of
Biostatistics with deep expertise in pharmacodynamic (PD) data
analysis to join our team on an ad hoc, per-study basis. This is a
high-impact, on-call opportunity for a statistician who thrives in
early-phase clinical research and wants to contribute strategic
value without committing to a full-time role. While initially
fractional, the position may evolve based on study load and team
needs—making it ideal for experienced professionals looking to
partner deeply without traditional constraints. Position Summary:
The Scientific Manager of Biostatistics is responsible for
supporting and advising clients on all aspects of PD data
collection and analysis. This role involves developing the PD
analysis sections of the SAP and shells for tables, listings, and
figures (TLFs), consulting with clients on PD analysis strategies,
and ensuring data quality and accuracy through review and
validation. This position requires strong pharmacodynamic (PD)
endpoint expertise, including extensive work with subjective
measures, VAS pain scales, and biomarker-driven analyses.
Responsibilities: Develop the PD Analysis section of the
Statistical Analysis Plan (SAP) and corresponding PD shells.
Consult with clients on PD analysis strategies and subject
allocation. Provide statistical design and methodology support for
PD-related endpoints. Ability to apply solid judgment to select and
implement appropriate statistical techniques based on study
objectives, data characteristics, and regulatory expectations
Review PD tables, figures, and listings (TFLs) to ensure quality
and consistency. Collaborate cross-functionally with internal teams
and clients. Participate in team meetings and strategic planning
discussions. Skills: Must be a clear, concise, and effective
communicator—able to translate complex statistical concepts into
actionable insights for clinical and cross-functional teams.
Professional attitude and strong interpersonal skills. Ability to
work well with a multi-disciplinary team of professionals.
Client-focused approach to work. Solution-focus and ability to
creatively solve problems and resolve issues. Ability to take
initiative and use sound judgment. Ability to acquire and apply
knowledge quickly. Flexible attitude and an ability to effectively
prioritize. Deep understanding of clinical research, statistical
principles, drug development process, and applicable regulatory
guidelines as they relate to complex phase I studies of CNS-acting
compounds. Significant Phase I clinical trial experience, including
Single Ascending Dose (SAD) and Multiple Ascending Dose (MAD) study
designs, execution, and analysis. Strong technical aptitude and
expertise in statistical analysis principles specific to PD data.
Working knowledge of SAS programming. Good computer skills
(Microsoft Word, Excel, and PowerPoint) and ability to understand
and adapt to various information technology (IT) systems.
Experience with Specific Data Types: VAS (Visual Analog Scales)
Pulmometry (Lung Function Testing) Psychedelic-related data and
endpoints Education and Experience: Master's degree in Statistics,
Biostatistics, or a related field (Ph.D. preferred). Minimum of 5
years of relevant experience as a statistician, with a focus in
pharmacodynamic data. Experience with CNS and early-phase studies
preferred. Prior CRO experience is a plus.
Keywords: Penfield Search Partners, Pittsfield , Scientific Manager of Biostatistics - Fractional (Ad Hoc) Remote, Science, Research & Development , Fairfield, Massachusetts
